Gynostemma pentaphyllum, also called jiaogulan, is a dioecious, herbaceous climbing vine of the family Cucurbitaceae (cucumber or gourd family). It is indigenous to the southern reaches of China, northern Vietnam, southern Korea, and Japan. Jiaogulan is best known as an herbal medicine reputed to have powerful antioxidant and adaptogenic effects purported to increase longevity. Pharmacological research has indicated a number of therapeutic qualities of jiaogulan, such as lowering cholesterol and high blood pressure, and strengthening immunity.